The Trojans will face the winner of UCLA and George Washington.
UCLA and Cal defeated USC, forcing the team to earn an at-large bid to the NCAAs.
USC will host the MPSF Tournament this weekend for the conference title.
Two top-ranked teams battled in a close match at Uytengsu Aquatics Center.
The Trojans look to stay on top after a crosstown rivalry match on Saturday.
The Trojans bested two top-15 ranked opponents over the weekend.
The top-ranked Trojans will host Cal on Saturday before traveling to UC Irvine on Sunday.
The top-ranked USC Trojans (25-1) picked up their 25th win of the season on Saturday at Uytengsu Aquatics Center in a 10-5 victory over the No. 5 Pacific Tigers (7-11).
Both water polo teams will host alumni players on Saturday at home.
The men’s water polo team beat Long Beach State and Pacific this past weekend.